Tangshan Solvents Trading Co.,Ltd was established in 2009 and located in China-Tangshan City, Hebei province. We are the exclusive agency of Shandong Wells Chemicals Co.,Ltd for export business, and also establish a long-term and stable cooperative relationship with many other chemical manufacturers in Shandong, Jiangsu provinces. Our factory covers 160,000 sq. m., and it holds 1 billion Yuan RMB of total assets. At present, there are 150 employees, more than 70 of which have college degree or above, 20 are senior engineers, and 30 are senior technicians.
Rich Product Variety
Our main products are series of Carbonates, such as: Propylene Carbonate, Dimethyl carbonate,Diethyl Carbonate, Propylene Glycol etc.;Solvents for Lithium battery such as battery grade of Propylene Carbonate, Ethylene Carbonate, Dimethyl Carbonate, Ethyl Methyl Carbonate,Diethyl Carbonate, Methyl propyl carbonate.
Wide Range of Product Uses
Our products are used in plastic industry, paint industry, lithium battery industry etc.
Production Equipment
At present, our group has more than 10 sets of processing lines which can produce more than 10 kinds of products. 100,000mt/per year of Propylene Oxide, 90,000mt/year of Propylene Carbonate, 5,000mt/year of Dimethyl carbonate together with 45,000mt/year of Propylene Glycol, 10,000mt/year of Sodium Methylate solution with Methanol, 10,000mt/year of DBE, 600,000mt/year MTP projects are in leading position in their area.
Leading Service
Our staff have many experience in technology and marketing .In order to keep competitive position still, Our products are sold to Europe, America, Japan, Korea and Southeast Asia and we have occupied the biggest domestic and abroad market share in these industries. Whether you want to buy Propylene Carbonate or Dimethyl carbonate, just send your requirements by email and we can customize the product for you.
What Is Sodium Methoxide Solution
Sodium methoxide solution is composed of 0.5M sodium methoxide in 0.5N methanol. It is a widely used organic base in organic synthesis.
Features of Sodium Methoxide Solution
Stability
The solid hydrolyzes in water to give methanol and sodium hydroxide. Indeed, samples of sodium methoxide are often contaminated with sodium hydroxide, which is difficult to detect. The compound absorbs carbon dioxide from the air to form methanol and sodium carbonate, thus diminishing the alkalinity of the base. ommercial batches of sodium methoxide show variable levels of degradation, and were a major source of irreproducibility when used in Suzuki reactions.
Safety
Sodium methoxide is highly caustic and reacts with water to give methanol, which is toxic and volatile.
Physical Appearance
Color: It is a colorless or slightly yellow liquid.
Odor: It emits a strong alcohol-like smell due to the presence of methanol.
Density: The density typically ranges between 0.9-1.0 g/cm³, depending on concentration and temperature.
Solubility
Solvent: Sodium methoxide is highly soluble in methanol. However, it reacts with water to form sodium hydroxide (NaOH) and methanol, leading to its decomposition in the presence of moisture.
PH
Basicity: Sodium methoxide is a strong base, which makes it highly caustic. It has a very high pH, typically around 14 when dissolved in methanol, and it can corrode materials if not handled properly.
Applications of Sodium Methoxide Solution
Organic synthesis
Sodium methoxide is a routinely used base in organic chemistry, applicable to the synthesis of numerous compounds ranging from pharmaceuticals to agrichemicals. As a base, it is employed in dehydrohalogenations and various condensations. It is also a nucleophile for the production of methyl ethers. It is used as an alkaline condensing agent and catalyst in organic synthesis, used in the synthesis of spices, dyes, etc., and is the raw material of vitamin B1, A and sulfadiazine.
Industrial applications
Sodium methoxide has a wide range of uses, mainly used in the production of sulfonamides, etc. Sodium methoxide is also a catalyst for organic synthesis, used in pesticide production and oil processing industry. There are two forms of sodium methoxide products in the supply industry: solid and liquid. The solid is pure sodium methoxide, and the liquid is methanol solution of sodium methoxide. The sodium methoxide content is 27.5~31%. Sodium methoxide is used as an initiator of anionic addition polymerization with ethylene oxide, forming a polyether with high molecular weight. Biodiesel is prepared from vegetable oils and animal fats (fatty acid triglycerides) by transesterification with methanol to give fatty acid methyl esters (FAMEs). Sodium methoxide acts as a catalyst for this reaction, but will combine with any free fatty acids present in the oil/fat feedstock to form soap byproducts.
Medicine and pesticides
It is used as a raw material for medicine and pesticides, and is an important raw material for the synthesis of drugs such as sulfamethoxazole, sulfamethoxazole, and sulfa synergist.
Other Uses
it is also used as a catalyst for processing edible fats and edible oils (especially lard) to change fats. The structure makes it suitable for use in margarine, etc., which must be removed in the final food. Mainly used as condensing agent, strong alkaline catalyst and methoxylation agent, used for the preparation of vitamin B1 and A, sulfadiazine and other drugs, and a small amount for pesticide production. It is also used as an analytical reagent and is widely used in industries such as spices and dyes.
Chemical composition and production method
Chemical Composition and Properties
Molecular Formula and Structure
The molecular formula of sodium methoxide is CH3ONa. It consists of a sodium cation (Na+) and a methoxide anion (CH3O-).
Physical Properties
Sodium methoxide is typically found in powder form. It is soluble in polar solvents like methanol and ethanol but insoluble in non-polar solvents like hexane. The compound is highly reactive and should be handled with caution.
Chemical Properties
It is a strong base and nucleophile, capable of deprotonating acidic hydrogens and participating in substitution and elimination reactions.
Production Methods
Industrial Synthesis
Sodium methoxide is commonly produced by reacting sodium metal with methanol. This process yields sodium methoxide and hydrogen gas as byproducts.
Laboratory Preparation
In the laboratory, sodium methoxide can be prepared by adding sodium metal to methanol under controlled conditions.
Safety Considerations
Hazards
Sodium methoxide is corrosive (UN 1431 Hazardous 4.2/PG 2) and can cause severe burns upon contact with skin or eyes. Inhalation of its dust or vapors can irritate the respiratory tract.
Handling Precautions
Proper personal protective equipment (PPE), including gloves, goggles, and a lab coat, should be worn when handling sodium methoxide. It should be used in a well-ventilated area, and contact with skin or eyes should be avoided.
Environmental Impact
Biodegradability
Sodium methoxide is biodegradable and does not persist in the environment. However, it should be handled and disposed of properly to prevent environmental contamination.
Disposal Methods
Disposal of sodium methoxide should be done according to local regulations. It can be neutralized with a weak acid before disposal or treated as hazardous waste.
Storage and Handling
Storage Conditions
As an II hazardous packing group, sodium methoxide should be stored in a cool, dry place away from moisture and air. It should be kept tightly sealed in its original container to prevent moisture absorption.
Handling Guidelines
When handling sodium methoxide, care should be taken to avoid exposure to moisture and air. It should be handled in a fume hood or well-ventilated area to prevent inhalation of dust or vapors.
Alternatives and Substitutes
Sodium Ethoxide
Sodium ethoxide, a closely related compound, can sometimes be used as an alternative to sodium methoxide in certain reactions.
Other Alkoxide Compounds
In some cases, other alkoxide compounds, such as potassium methoxide or potassium tert-butoxide, may be used as substitutes depending on the specific requirements of the reaction.
Regulatory Status
Sodium methoxide is subject to regulations regarding its production, handling, and transportation due to its hazardous nature. It is classified as a hazardous substance by regulatory agencies.
How to Use Sodium Methoxide Solution
The effect of methanol solution of sodium methoxide
Methanol solution of sodium methoxide is one of the commonly used reagents in the laboratory. It is usually used as a reducing agent, condensing agent, reductive coupling agent, etc. in various organic synthesis reactions. In experimental operations, methanol solution of sodium methoxide is also often used to prepare organic substances such as sodium methanolate, sodium acetate, and sodium acetate.
Precautions for methanol solution of sodium methoxide
1. The methanol solution of sodium methoxide should be stored in a cool, ventilated, dry place, and avoid contact with oxygen, acids and other substances to avoid explosion.
2. Safety protective gear should be worn during operation, such as gloves, glasses, etc.
3. Methanol solution of sodium methoxide cannot be mixed directly with water, otherwise it will cause violent reaction or even explosion.
4. The bottle should be shaken thoroughly before use to ensure uniform mixing of sodium methoxide.
Operation steps of methanol solution of sodium methoxide
1. Take out the required amount of methanol solution of sodium methoxide and dilute or mix according to the experimental requirements.
2. Slowly drop the methanol solution of sodium methoxide into the container with the reaction materials, and mix with a magnetic stirrer.
3. If the reaction needs to be heated, the reaction vessel should be placed in a water bath for heating first to avoid accidents.
4. After the reaction, the reaction solution should be stored in a waste liquid collection container in time to avoid environmental pollution.
Frequently Asked Questions